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Author  |
De Luca, F.; Cametti, C.; Zimatore, G.; Maraviglia, B.; Pachi, A. |
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Title |
Use of low-frequency electrical impedance measurements to determine phospholipid content in amniotic fluid |
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Journal Article |
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Year |
1996 |
Publication |
Physics in Medicine and Biology |
Abbreviated Journal |
Phys Med Biol |
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Volume |
41 |
Issue |
9 |
Pages |
1863-1869 |
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Keywords |
*Amniocentesis; Amniotic Fluid/*chemistry/*physiology; Electric Conductivity; Electric Impedance; Female; Gestational Age; Humans; Phospholipids/*analysis; Pregnancy; Pregnancy Trimester, Second; Pregnancy Trimester, Third |
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Abstract |
In this report we propose a new method for an in vitro test of the foetal lung maturity based on the measurement of the electrical conductivity of the overall amniotic fluid obtained from transabdominal amniocentesis, since this quantity can be linked to a first approximation in a very simple way to the phospholipid content. We have carried out measurements of 85 different samples of amniotic fluid as a function of gestation weeks and we have observed a pronounced change of the electrical conductivity that reflects the increase in the phospholipid concentration occurring at the end of normal pregnancies. The method could be further developed to obtain similar information on in vivo experiments by means of bioelectric impedance tomography, taking advantage of the frequency dependence of the tissue electrical impedance. |
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Address |
Dipartimento di Fisica, Universita La Sapienza, Roma, Italy |
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Language |
English |
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Original Title |
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Series Volume |
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Edition |
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ISSN |
0031-9155 |
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Area |
WP2 Exposure measurements |
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Notes |
PMID:8884917 |
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no |
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Call Number |
CNR-ISIB @ paolo.ravazzani @ |
Serial |
221 |
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