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Author (up) Capri, M.; Mesirca, P.; Remondini, D.; Carosella, S.; Pasi, S.; Castellani, G.; Franceschi, C.; Bersani, F. url  doi
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  Title 50 Hz sinusoidal magnetic fields do not affect human lymphocyte activation and proliferation in vitro Type Journal Article
  Year 2004 Publication Physical Biology Abbreviated Journal Phys Biol  
  Volume 1 Issue 3-4 Pages 211-219  
  Keywords Adult; Aged; Cell Cycle; Cell Proliferation/*radiation effects; Flow Cytometry; Humans; Lymphocyte Activation/*radiation effects; *Magnetics; Phenotype  
  Abstract In the last 30 years, an increasing public concern about the possible harmful effects of electromagnetic fields generated by power lines and domestic appliances has pushed the scientific community to search for a correct and comprehensive answer to this problem. In this work the effects of exposure to 50 Hz sinusoidal magnetic fields, with a magnetic flux density of 0.05 mT and 2.5 mT (peak values), were studied on human peripheral blood mononuclear cells (PBMCs) collected from healthy young and elderly donors. Cell activation and proliferation were investigated by using flow cytometry techniques and 3H-TdR incorporation assays, respectively. The results obtained indicated that exposure to the fields altered neither DNA synthesis nor the capacity of lymphocytes to enter the activation phase and progress into the cell cycle. Thus, the conclusions are that two important functional phases of human lymphocytes, such as activation and proliferation, are not affected by exposures to 50 Hz magnetic fields similar to those found under power lines.  
  Address Department of Experimental Pathology, Via S Giacomo 12, University of Bologna, 40126 Bologna, Italy  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1478-3967 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:16204841 Approved no  
  Call Number IT'IS @ evaj @ Serial 291  
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